综合一区欧美国产,99国产麻豆免费精品,九九精品黄色录像,亚洲激情青青草,久久亚洲熟妇熟,中文字幕av在线播放,国产一区二区卡,九九久久国产精品,久久精品视频免费

Global EditionASIA 中文雙語Fran?ais
China
Home / China / Innovation

Chinese scientists develop broad-spectrum nanobodies for tick fever treatment

Xinhua | Updated: 2025-11-21 10:23
Share
Share - WeChat
Professor Wu Xilin (C) works with his team at Nanjing University Medical School in Nanjing, East China's Jiangsu province, Nov 20, 2025. [Photo/Nanjing University/Handout via Xinhua]

NANJING -- A Chinese research team has developed a combination of nanobodies that shows potent and broad efficacy against Severe Fever with Thrombocytopenia Syndrome (SFTS), a severe infectious disease commonly known as tick fever.

With global incidence of SFTS rising and no specific treatments currently available, this breakthrough offers a potential therapeutic solution.

The study, led by Professor Wu Xilin and his team at Nanjing University Medical School in collaboration with several domestic institutions, was published this Thursday (Beijing Time) as the cover story in the journal Science Translational Medicine.

SFTS infections often occur from April to September when people are bitten by ticks in grassy or wild areas. The disease can lead to severe symptoms such as high fever and a sharp drop in platelet count.

Previously, researchers at Nanjing University had isolated first-generation nanobodies against the virus from alpacas, which showed preliminary efficacy in trials done on mice.

To address the challenge posed by the multiple subtypes of SFTS virus, the researchers adopted a "cocktail therapy" approach. They immunized alpacas with antigens from different viral subtypes and screened for two potent nanobodies that target distinct conserved viral sites and block infection. These nanobodies were then combined into a single treatment.

In tests, infected ferrets treated with this nanobody cocktail all survived. Their viral loads dropped to undetectable levels, with significant improvements in platelet counts and reduced tissue damage.

The research team has initiated preclinical research on this nanobody combination. "We hope to deliver a drug solution that can both treat and prevent SFTS," Wu said.

Top
BACK TO THE TOP
English
Copyright 1995 - . All rights reserved. The content (including but not limited to text, photo, multimedia information, etc) published in this site belongs to China Daily Information Co (CDIC). Without written authorization from CDIC, such content shall not be republished or used in any form. Note: Browsers with 1024*768 or higher resolution are suggested for this site.
License for publishing multimedia online 0108263

Registration Number: 130349
FOLLOW US
 
榆树市| 旬阳县| 浏阳市| 轮台县| 蒙城县| 宁远县| 泸溪县| 岳池县| 麻城市| 扬州市| 威信县| 临颍县| 霍林郭勒市| 哈巴河县| 安康市| 密山市| 松潘县| 黄石市| 盘锦市| 巴塘县| 瑞丽市| 隆林| 桓台县| 南川市| 宜兰市| 乌苏市| 屯昌县| 扶沟县| 浦北县| 梓潼县| 常德市| 宁国市| 禹州市| 岗巴县| 湟中县| 同德县| 隆安县| 漳平市| 航空| 布拖县| 化隆|